1 Molecular formula C2HsNO2
2 Molecular weight 75.07
3 Physical—chemistry property:White monoclinic crystcl or hexagonal crystal or white
crystalline powder .Odourless with special sweet taste. Relative density is 1.1607.
melting point is 248℃ .(dissolve) Pk’1(COOH)is 2.34, Pk’2(N+H3) is 9.60. Soluble in
water,and Solubility is :25℃,25g/100ml:50℃,39.1g/100ml:75℃,54.4g/100ml:100℃,67.2g/
100ml.hardly soluble in ethanol and solubility is 0.06g in 100g ethanol absolute hardly
soluble inAcetone and diethyl enther. React with hydrochloric and become hydrochloride.
pH(50g/l solution,25℃)=5.5~7.0
4 Mainly usage:1.Used as the medicine material in study of amino acid metabolism for medical
microbiology and blological chemistry.2.Used as the amino acid synthetic source of aureomycin
buffer,antipakinsonism agent,L—dopa,vitamin B6 and threonine.3.Used as nutritional transfusion
of amino acid.4.Used as the material for cephalosporin,and intermediate for synthesis of imidazole
Acetic.5.Used as the material for cosmetics.
5 Qualit specification:
1 American Pharmacopoeia 34th
Identification test:infrared spectra test up to standar
Assay 98.5~101.5%
Chloride(CI) ≦0.007%
Heavy metal(Pb) ≦0.0020%
Loss on drying ≦0.20%
Residue on ignition ≦0.10%
Sulfated ash ≦0.0065%
Readily hydrolsable substance up to standard
2.European Pharmacopoeia 7.0 edition
Dentification test:
Infrared spectrum test up to standard
Positive ninhydrin ≦0.50%
Assday 98.5~101.5%
Chloride(CI) ≦0.0075%
Heavy metal(Pb) ≦0.001%
Loss on drying ≦0.50%
Sulfated ash ≦0.10%
Ph value 5.9~6.4
Appearance of solution clear and not in shade deeper than
Contrast solution
Appearance white crystallin powder
Solubility readily dissolve in water,slghtly dissolve
In alcohol(96%),showing polymorphism
3.National Pharmacopoeia of China 2010 Edition. 2nd part
Appearance white crystalline powder
Solubility readily dissolve in water,hardly dissolve in diethyl and Ethanol
Identification test (infrared spectra test) up to standard
PH value 5.6~6.5
Light transmittance of solution ≦98.0%
Assay ≦99.0%
Chloride(CI) ≦0.007%
Sulfated ash ≦0.006%
Ammonium salt ≦0.02%